N-Methylformanilide

N-Methylformanilide, chemical name N-phenyl-N-methylformamide, has molecular formula C8H9NO, molecular weight 135.17 and CAS number 93-61-8. It is a colorless to pale yellow liquid at room temperature that solidifies on cooling (melting point 14-15°C), with a boiling point of 243°C, a flash point of 126°C; it is soluble in ethanol, ether and acetone and slightly soluble in water (see specifications). This product serves as the formylation reagent in the Vilsmeier-Haack reaction, introducing a formyl group into reactive aromatic compounds; the reaction is an important method for synthesizing aromatic aldehydes. The product is supplied at an assay of ≥99.0% with residue on ignition ≤0.10% (see specifications). The figures on this page are routine release control items; this product is not registered as a pharmaceutical excipient, and suitability for pharmaceutical use must be evaluated by the buyer according to drug regulatory requirements.

Primarily used in organic synthesis as a formylation reagent in the Vilsmeier-Haack reaction, introducing a formyl group into reactive aromatic compounds (arenes, heterocycles, enamines); the reaction is an important method for synthesizing aromatic aldehydes. Also used as an organic synthesis intermediate in the production of dyes, pesticides, pharmaceuticals and other fine chemicals — for pharmaceutical directions, registration and compliance requirements are evaluated and confirmed by the buyer — and as a solvent or co-solvent in specialized organic reactions.

As a formylation reagent in the Vilsmeier-Haack reaction, it introduces a formyl group into reactive aromatic compounds (arenes, heterocycles, enamines); the reaction is an important method for synthesizing aromatic aldehydes, and substrate suitability and reaction conditions follow published methods and the customer's own process validation. Figures such as assay ≥99.0% and moisture ≤0.2% are listed under specifications and can be reviewed before charging.

It is also used as an organic synthesis intermediate in the production of dyes, pesticides, pharmaceuticals and other fine chemicals; for pharmaceutical directions, registration and compliance requirements are evaluated and confirmed by the buyer. Batch data can be confirmed with our sales team during inquiry.

It can be used as a solvent or co-solvent in specialized organic reactions; the boiling point of 243°C, flash point of 126°C and slight water solubility (see specifications) serve as reference points for solvent selection, with compatibility confirmed through the customer's process validation.